Influencing Factors of Myocardial Microcirculation Perfusion and Prediction Model Construction in Acute STEMI Patients after Intervention Surgery
LIU Xiaoxiao
ZHANG Wanling
YU He
SONG Bo
SUN Hongzhou
Abstract：Objective:To explore the influencing factors of myocardial microcirculation perfusion in patients with acute ST-segment elevation myocardial infarction(STEMI)after interventional therapy and to construct a predictive model based on ultrasound assessment.Method:A total of 135 patients with acute STEMI who underwent interventional surgery were included.According to the postoperative myocardial microcirculation perfusion status,the patients were divided into normal group(54 cases)and abnormal group(81 cases).The general data,coronary angiography data and echocardiographic indicators of the two groups were compared.Multivariate analysis was conducted to explore the influencing factors of abnormal myocardial microcirculation perfusion in patients with acute STEMI after interventional surgery,and the efficacy of the predictive model for abnormal myocardial microcirculation perfusion in patients with acute STEMI after interventional surgery was analyzed.Results:The results showed that the peak level of myocardial troponin,the proportion of culprit vessels being the left anterior descending artery,the proportion of single-vessel disease,the wall motion score index and the ratio of early diastolic transmitral velocity to early diastolic mitral annular velocity(E/Em)were significantly higher in the abnormal group than those in the normal group(P＜0.05).The results of multivariate analysis showed that the peak level of cardiac troponin,culprit vessel,mitral valve E/Em,wall motion score,and deceleration time of mitral valve E wave were independent influencing factors of myocardial perfusion abnormality(P＜0.05).Conclusion:The occurrence of myocardial microcirculatory perfusion abnormalities in acute STEMI patients after interventional surgery is independently influenced by the peak level of cardiac troponin,culprit vessel type,mitral valve E/Em,wall motion integral,and mitral valve E peak deceleration time.The model built based on the above factors shows better efficacy in predicting the occurrence of abnormal myocardial microcirculation perfusion after interventional surgery.
Keywords：ST-segment elevation myocardial infarctioninterventional surgerymyocardial microcirculationpredictive value
Publication Date：2025-04-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1197-1202 )