Exploring the Mechanism of Ferroptosis in Atherosclerosis Based on the Theory of"Blood Stasis"
GAO Kun
LI Lizhi
WANG Lianhua
Abstract：Based on the theory of 'blood stasis', this study explores the mechanism of ferroptosis in atherosclerosis. By following the pathogenesis characteristics, traditional Chinese medicine is used to intervene in ferroptosis, promoting the clearance of lipid peroxidation products, thereby improving endothelial function and alleviating the condition of atherosclerosis. The 'Qi' in traditional Chinese medicine has some functional relevance with mitochondria in modern medicine. The normal flow of blood in the vascular system depends on the coordinated regulation of 'heart, blood, and vessels'. The mechanism of ferroptosis in atherosclerosis highly aligns with the theory of 'blood stasis'.
Keywords：atherosclerosisblood stasisferroptosistraditional Chinese medicinemitochondriareview
Publication Date：2025-02-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 392-396 )