Meta-analysis of Banxia Baizhu Tianma Decoction for the Treatment of Hypertension in Patients with Overweight or Obesity
GUO Yaxin
ZHAO Fangfang
ZHAO Xiaosen
LU Lijie
CHEN Luying
WANG Yaojian
JIANG Yuerong
Abstract：Objective:To evalute the efficacy and safety of Banxia Baizhu Tianma Decoction for the treatment of hypertension with overweight/obesity.Methods:The databases include CNKI,WanFang,VIP,SinoMed,PubMed,EMbase,the Cochrane Library,Web of Science,and clinical trials registry platforms were searched to collect randomized controlled trials(RCTs)about Banxia Baizhu Tianma Decoction for treatment of hypertension with overweight/obesity.Then Meta-analysis was performed using RevMan 5.4 software.Results:A total of 9 RCTs studies involving 873 patients were included.The results of Meta-analysis showed that compared with the control group,the mean sitting systolic blood pressure(msSBP)(MD=-7.60,95%CI-8.77--6.42,P＜0.000 01),the mean sitting diastolic blood pressure(msDBP)(MD=-5.15,95%CI-6.82--3.49,P＜0.000 01),and the body mass index(BMI)(MD=-2.74,95%CI-4.74--0.73,P=0.007)were lower in the treatment group.And the efficiency of traditional Chinese Medicine(TCM)syndrome(RR=1.19,95%CI 1.08-1.31,P=0.000 4)was higher in the treatment group.However,there was no significant difference in levels of blood lipid and the adverse reactions between two groups.Conclusion:The current evidence shows that Banxia Baizhu Tianma Decoction for the treatment of hypertension with overweight/obesity was effective and safety.
Keywords：hypertensionoverweightobesityBanxia Baizhu Tianma DecoctionMeta-analysis
Publication Date：2025-02-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 321-327 )