Ultrasound 2D-STI Technology for Prediction of Major Adverse Cardiac Events after Percutaneous Coronary Intervention in Acute Myocardial Infarction
YOU Donghua
JIA Baoxia
CHEN Jinhua
Abstract：Objective: To explore the predictive value of ultrasound two-dimensional speckle tracking imaging (2D-STI) technology for major adverse cardiac events (MACE) in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). Methods: A total of 126 AMI patients who underwent PCI at our hospital between March 2022 and March 2023 were analyzed. According to whether MACE occurred, they were divided into the MACE group (23 cases) and the non-MACE group (nMACE, 103 cases). All subjects received ultrasound 2D-STI and biochemical tests before discharge. The general data, ultrasound parameters, and biochemical data of the two groups were compared. The correlations between the 2D-STI parameters, including global circumferential strain (GCS), global radial strain (GRS), and global longitudinal strain (GLS), with left ventricular ejection fraction (LVEF) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) were analyzed. The influencing factors of MACE within 12 months after PCI in AMI patients were analyzed, and the predictive value of GCS, GRS, and GLS for MACE was evaluated. Results: There were statistically significant differences in LVEF, GCS, GRS, GLS, and NT-proBNP between the MACE group and the nMACE group (P < 0.05). The 2D-STI parameters GCS, GRS, and GLS were positively correlated with LVEF (r values were 0.387, 0.401, 0.355, P values were 0.016, 0.009, 0.019, respectively) and negatively correlated with NT-proBNP (r values were -0.413, -0.514, -0.451, P values were 0.007, 0.001, 0.010, respectively). Multivariate logistic regression analysis showed that LVEF, NT-proBNP, GCS, GRS, and GLS were all risk factors for MACE within 12 months after PCI in AMI patients. The receiver operating characteristic (ROC) curve analysis showed that the areas under the curve for predicting MACE by GCS, GRS, and GLS were 0.801, 0.780, and 0.824, respectively. Conclusion: The 2D-STI parameters GCS, GRS, and GLS have high clinical value in predicting MACE in AMI patients after PCI within 12 months.
Keywords：acute myocardial infarctionpercutaneous coronary interventionmajor adverse cardiac eventsultrasoundtwo dimensional spot tracking
Publication Date：2025-01-15
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 105-109 )