Effect of Chinese Patent Medicine on Cardiac Neurosis:a Network Meta-analysis
QIN Zelin
LI Ruoqi
TAN Chao
DUAN Wenhui
Abstract：Objective:The effect of Chinese patent medicine on cardiac neurosis was evaluated by network meta-analysis.Methods:Randomized controlled trials of proprietary Chinese patent medicines for cardiac neurosis were searched from PubMed,Web of Science,EMbase,the Cochrane Library,China National Knowledge Infrastructure(CNKI),WanFang Database and VIP Chinese Full-text Database of Scientific and Technological Journals(VIP)from the establishment of the database to April 1,2023.RoB2 was used for bias risk assessment and Stata 17SE was used for network meta-analysis.Results:A total of 48 literatures were finally included,involving 9 kinds of Chinese patent medicines including Wenxin Granules,Shugan Jieyu Capsules,Shensong Yangxin Capsules,Xinkeshu Tablets,Yangxin Tablets,Xiaoyao Pills,Yixinshu Capsules,Wuling Capsules,and Baizi Yangxin Pills.The results of network meta-analysis showed that the total effective rate of Shugan Jieyu Capsule was best one.Wenxin Granule was the best in improving somatization symptom.Xinkeshu Tablet was the best for improving anxiety.Yixinshu Capsule was the best for improving depression.Conclusion:The existing evidence show that the curative effect of Chinese patent medicine combined with conventional Western medicine for the treatment of cardiac neurosis are superior to that of conventional Western medicine alone.
Keywords：cardiac neurosisChinese patent medicinenetwork Meta-analysis
Publication Date：2024-08-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：12( 2696-2707 )