Predictive Value of Atherogenic Index of Plasma for the Degree of Coronary Artery Disease in Patients with Coronary Heart Disease Combined with Type 2 Diabetes Mellitus
LI Tong
XU Chenxi
WANG Yubi
LIU Anxiang
LU Xiaoyan
Abstract：Objective:To observe the predictive value of atherogenic index of plasma(AIP)for the degree of coronary artery disease in patients with coronary heart disease(CHD)combined with type 2 diabetes mellitus(T2DM).Methods:Two hundred and eight patients with from January 1,2018 to December 1,2020 were selected,there were 95 cases in the CHD group and 113 cases in the CHD combined with T2DM group.The general data,biochemical indexes,and coronary angiography results were collected,and compared between two groups.The number of coronary artery lesion branches in different coronary arteries were analyzed.Results:AIP was higher in the CHD combined T2DM group than that in the CHD group(P =0.044).According to the number of coronary artery lesion branches,patients with CHD combined with T2DM were divided into single vessel disease group,double vessel disease group,and triple vessel disease group.The AIP and triacylglycerol(TG)between three groups were compared,and the difference was statistically significant(P<0.05).The multivariate Logistic regression model showed that AIP was an independent risk factor affecting the number of coronary artery lesion branches(OR=15.218).The receiver operating characteristic(ROC)curve showed that AIP was a better predictor of the number of coronary artery lesion branches[ROC area under the curve(AUC)=0.684,P =0.009].Conclusion:AIP was a risk factor for CHD combined with T2DM,and it was an independent risk factor for evaluating the number of coronary artery lesion branches in patients with CHD combined with T2DM.It could be used as a feasible index to predict the degree of coronary artery disease.
Keywords：coronary heart diseasetype 2 diabetes mellitusatherogenic index of plasmanumber of diseased branchespredictive value
Publication Date：2023-12-16
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 4496-4500 )