The Influence of Acupuncture at Huiyang Jiuzhen Point on ET,EDHF and NO levels in Patients with Stroke Sequelae

JIANG Shuhong; YU Zheng; ZHU Minghao

doi:10.12102/j.issn.1672-1349.2019.02.005

Abstract：Objective To investigate the effect of acupuncture at Huiyang Jiuzhen point on serum endothelin(ET),endothelial-derived hyperpolarizing factor(EDHF)and nitric oxide(NO)levels in patients with stroke sequelae.Methods Ninety-four patients with stroke sequelae admitted to our hospital from December 2014 to October 2016 were randomly divided into two groups:control group (n =47)treated with routine treatment,and treatment group(n =47)treated with acupuncture at Huiyang Jiuzhen point in the basis of routine treatment for 4 weeks.The clinical efficacy,neurological deficit,and physiological function were compared between the two groups,and ET,EDHF and NO levels were detected by enzyme linked immunosorbent assay(ELISA).Results The total clinical effective rate was significantly higher in treatment group than that in control group(95.74％ vs.76.60％,χ2=7.231,P =0.007).After treatment,the neurological deficit scores were decreased and the physiological function scores were increased,which were better in the treatment group than that in the control group(P <0.05).The level of ET after treatment was lower than that before treatment, while the levels of EDHF and NO were higher than those before treatment,which were better in the treatment group than that in the control group(P <0.05).The scores of quality of life in the two groups after treatment were higher than those before treatment, which were higher in the treatment group than that in the control group(P <0.05).Conclusion Acupuncture at Huiyang Jiuzhen point has a good clinical effect in treating stroke sequelae.It can improve the neurological and physiological function of patients,regulate vascular endothelial cell function and improve the quality of life.