Effect of Total Parathyroidectomy and Total Parathyroidectomy with Parathyroid Autotransplantation in Treatment of Uremic Secondary Hyperparathyroidism
Abstract:Objective: To compare the efficacy of total parathyroidectomy(tPTX)and total parathyroidectomy(tPTX)with parathyroid autotransplantation(AT)in treatment of uremic patients with secondary hyperparathyroidism (SHPT). Methods: The clinical data of 64 patients of uremic SHPT who underwent with tPTX (n = 31)and tPTX + AT (n = 33)in our hospital from January 2009 to May 2014 were analyzed. Intact parathyroid hormone(iPTH), serum calcium, phosphorus and recurrence rate were compared before and after surgery. And compare the curative effect of two ways. Results: Compare with the preoperative patients, the iPTH, serum calcium and serum phosphorus were significant reduced, and the symptom was eased obviously in the postoperative patient in both tPTX and tPTX + AT group. Compared with tPTX group, tPTX + AT has higher serum calcium value, but also higher recurrence rate. Conclusion: Both tPTX and tPTX + AT surgical methods have their own advantages and disadvantages. Two methods are relatively safe and effective method in the treatment of uremic patients with SHPT.
Keywords:ParathyroidectomyAutotransplantationSecondary hyperparathyroidism Uremic
Publication Date:2018-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 866-869 )