Relationship between Traditional Chinese Medicine Syndromes and Target Organ Damage in 443 Patients with Hypertention
Lu Cheng
Song Lei
Liu Yongming
Abstract：Objective To study the relationships between traditional Chinese medicine (TCM) syndromes and target organ damage in patients with hypertention. Methods Four hundreds and forty-three patients with hypertention were selected.The data on TCM di-agnosis and target organ damage (carotid atherosclerosis,left ventricular hypertrophy,and serum creatinine levels) were collected. The target organ damages were compared and analyzed in patients with different syndromes. Results The proportion of TCM syndromes in patients with hypertension was as follows in descending order:liver-kidney yin deficiency syndrome,qi-yin deficiency syndrome, yang deficiency syndrome,phlegm-dampness syndrome,liver-yang hyperactivity syndrome. The 24-hour diastolic blood pressure (24 h DBP) and 24-hour mean blood pressure (24 h MBP) in phlegm-dampness syndrome were higher than those in liver-kidney yin deficiency syndrome ( P＜0.05). The average heart rate in liver-kidney yin deficiency syndrome and yang deficiency syndrome were lower than that in qi-yin deficiency syndrome ( P＜0.05). There was no significant difference in the carotid intima-media thick-ness (IMT) level among the different syndromes ( P＞0.05). The interventricular septal thickness at end diastole (IVSd) in qi and yin deficiency syndrome was larger than that in liver-kidney yin deficiency syndrome ( P＜0.05). There was no significant difference in the levels of creatinine,uric acid and 24-hour urinary protein among the different syndromes ( P＞0.05). Conclusion The main syn-drome is liver-kidney yin deficiency syndrome in patients with hypertention. The highest blood pressure is found in hypertensive pa-tients with phlegm-dampness syndrome,and the lowest blood pressure is found in liver-yang hyperactivity syndrome.The severity of carotid atherosclerosis is the most serious in patients with liver-kidney yin deficiency syndrome. Left ventricular hypertrophy is heav-ier in patients with phlegm-dampness syndrome. The highest value of serum creatinine is found in patients with liver-kidney yin de-ficiency syndrome. The quantification of 24-hour urine protein is the highest in liver-yang hyperactivity syndrome.
Keywords：hypertentiontraditional Chinese medicine syndromestarget organ damagecarotid intima-media thicknessserum creati-nineuric acidurinary protein
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1313-1316 )