Effect of Auricular Acupoint Shenmen (TF4) Seeds Therapy on Amplitude of Low-Frequency Fluctuation in Patients with Migraine
Gong Yuanyuan
Nie Bo
Zhang Hong
Liu Lei
Song Lianying
Pan Huihui
Zhang Liping
Zhou Lanzhen
Kang Shu
Kong Linggang
Song Zhichao
Du Congde
Jiang Gendi
Wang Jun
Abstract：Objective To study the influence of auricular acupoint Shenmen (TF4) seeds therapy on resting-state brain neural activity in patients with migraine based on functional magnetic resonance imaging(fMRI).Methods Nine patients with migraine were selected as treatment group,and 9 healthy subjects were as healthy control group.The resting-state whole brain functional images were collected by fMRI technology before and after auricular acupoint Shenmen (TF4) seeds therapy.Data were statistically analyzed using REST software.Results Before the intervention,amplitude of low-frequency fluctuation (ALFF) of left inferior frontal gyrus in the treatment group was significant lower than that in healthy control group.ALFF of left peripheral cortex of the cleft,left supplementary motor area in the treatment group was significant higher than that in healthy control group(P ＜0.005).After the intervention,ALFF of Bilateral superior frontal gyrus,left middle frontal gyrus in the treatment group was lower than that inhealthy control group.ALFF of left inferior occipital gyrus,right fusiform gyrus in the treatment group was significant higher than that in healthy control group (P ＜0.005).Conclusion The related brain functional areas participate in the regulation of pain,visual perception respectively enhanced and weakened in paroxysm interval of patients with migraine,supporting the central hypothesis of migraine.Stimulating auricular acupoint Shenmen (TF4) can enhance visual related brain function.
Keywords：migrainefunctional magnetic resonance imagingamplitude of low-frequency fluctuationauricular acupoint Shenmen (TF4)seeds therapy
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 276-280 )