Effect of Qigui Jiannao Prescription on Serum amyloid-β Protein and Cognitive Ability in Patients with Alzheimer's Disease
Wang Yinlong
Shan Tieying
Shan Tieqiang
Wang Xuedan
Su Anying
Pan Xiulan
Yan Yingjie
Liu Fulai
Abstract：Objective To explore the effects and clinical significance of Qigui Jiannao prescription (QJP) on the level of serum amylold β protein and cognitive ability in patients with Alzheimer's disease (AD).Methods Sixty patients with AD were collected in hospital,and randomly divided into two groups;control group (n =30) treated with Naofukang,and treatment group (n =30) treated with QJP for 6 months.The content of serum amylold-β were detected before and after treatment respectively,and the mental retardation degree was evaluated by simple intelligence status scale.Results Compared with that before treatment,the serum level of amyloid-β protein in two groups were significantly decreased after treatment (P ＜0.05),while the simple mental state scale scores were markedly increased after treatment (P ＜0.05).There was no significantly differences between control group and treatment group (P ＞0.05).Conclusion QJP can improve the cognitive abilities in patients with AD,which can improve the content of serum amyloid-β protein in patients with AD.
Keywords：Alzheimer's diseaseQigui Jiannao prescriptionNaofukangamyloid-β proteincognitive ability
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 2813-2815 )