Analysis on Risk Factors of Worsening Renal Function in Patients with Chronic Heart Failure of Coronary Heart Disease
Yang Xueqing
Wang Xian
Abstract：Objective To explore the risk factors of worsening renal function (WRF) in patients with chronic heart failure (CHF) of coronary heart disease (CHD).Methods Two hundreds and sixty-eight patients with CHF of CHD were divided into cardiorenal syndrome (CRS) group (n =120) and non-CRS group (n =148) based on the occurrence of WRF.The clinical medical records and test results of these hospitalized patients were recorded in detail.At the same time,the possible factors leading to CRS were selected with the help of literature and medical records.All the data were pulled into a computer after proofread and then we calculated results by conducting the single factor analysis and the multivariate regression analysis.Results The results showed the high risk factors of WRF in patients with CHF of CHD were New York Heart Association (NYHA) Classification Ⅲ ～ Ⅳ,history of diabetes and hypertension,serum creatinine and(Scr),and Cystatin C (CysC) by a multivariate regression analysis.Conclusion NYHA Ⅲ ～ Ⅳ,history of diabetes and hypertension,Scr,and CysC were most closely associated with WRF in patients with CHF of CHD.
Keywords：coronary heart diseaseheart failureworsening renal functionNew York Heart Association Classificationserum creatinineCystatin C
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 2521-2525 )