Clinical Observation on Creatine Phosphate Sodium and Montelukast Sodium in the Treatment of Children with Bronchiolitis Complicated with Myocardial Damage
Chen Jia
Abstract：Objective To investigate the clinical efficacy of creatine phosphate sodium and montelukast in the treatment of children with bronchiolitis complicated with myocardial damage and its effect of serum myocardial enzyme spectrum.Methods Eighty-six cases of children with bronchiolitis complicated with myocardial damage in our hospital from January 2015 to January 2016 were randomly divided into two groups:control group (n =43) treated with montelukast sodium,and treatment group (n =43) treated with creatine phosphate sodium and montelukast in the basis of routine treatment for 1 week.The clinical curative effect,the expression levels of myocardial enzymes,creatine kinase (CK),creatine kinase isoenzyme (CK-MB),aspartate aminotransferase (AST),lactate dehydrogenase (LDH),hydroxybutyric dehydrogenase (HBDH) before and after the treatment,and adverse reaction were observed.Results The total clinical effective rate was significantly higher in treatment group than that in control group (93.0％ vs 74.4％,P ＜0.05).After treatment,the levels of serum CK,CK-MB,AST,LDH and HBDH improved in two groups,which was better in treatment group than that in control group (P ＜0.05).There was no obvious adverse reactions in two groups.Conclusion Creatine phosphate sodium and montelukast sodium has significant effect,which can significantly improve the levels of myocardial enzymes in children with bronchiolitis complicated with myocardial damage.
Keywords：bronchiolitismyocardial damagecreatine phosphate sodiummontelukastmyocardial enzymes
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 2431-2433 )