Effect of Sanye Tablets on Serum Apolipoprotein A5 in Mice with Hyperlipidemia
Lu Meijuan
Wang Baohe
Xu Qiang
Zhuang Jianguo
Abstract:Objective To observe the effect of Sanye tablets (SYT) on serum apolipoprotein A5 (ApoA5) in mice with hyperlipidemia.Methods The hyperlipidemia mice model were established by high fat diet.After giving SYT,enofibrate and Xuezhikang for 30 days,the serum ApoA5 level was detected by ELISA method.Results There was differences in the content of ApoA5 between model group and the normal control group,Xuezhikang group,fenofibrate group,SYT low dose group (P <0.05 or P <0.01).There was no difference in the content of ApoA5 between fenofibrate group and Xuezhikang group,SYT high dose group,SYT low dose group (P >0.05).There was no difference in the content of ApoA5 between SYT high dose group and SYT low dose group (P > 0.05).Conclusion SYT has lipid lowering effect,which is likely to be affected by ApoA5.The lipid lowering effect of SYT is not dose dependent.
Keywords:hyperlipidemiaSanye tabletsapolipoprotein A5blood lipidsphlegm
Publication Date:2017-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 2390-2392 )