Effects of Compound Wenban Decoction and Enhanced External Counterpulsation on the Levels of Serum NO and ET-1 in Patients with Unstable Angina Pectoris
Zhao Ling
Gong Lihong
Abstract：Objective To observe the effects of compound Wenban decoction (CWD) and enhanced external counterpulsation (EECP) on the levels of serum nitric oxide (NO) and endothelin-1 (ET-1) in patients:with unstable angina pectoris (UAP).Methods One hundred and twenty patients with UAP were collected and randomly divided into two groups:control group (n =60) treated with routine treatment plus CWD,and treatment group (n =60) treated with routine treatment plus CWD and EECP for 4 weeks.The changes of angina pectoris symptoms,Chinese medical syndrome and the levels of serum NO and ET-1 were observed.Results After treatment,the curative effects of angina pectoris symptom,and Chinese medical syndrome in treatment group were obviously better than that in control group (P ＜0.05).The scores of Chinese medical syndrome declined obviously in two groups,which was obviously better in treatment group than that in control group (P ＜0.05).After treatment,the levels of serum NO and ET-1 improved obviously in two groups,which was obviously better in treatment group than that in control group (P ＜0.05).Conclusion CWD and EECP can improve the symptoms of angina pectoris and Chinese medical syndrome in patients with UAP and regulate the levels of serum NO and ET-1.
Keywords：coronary heart diseaseunstable angina pectorisenhanced external counterpulsationnitric oxideendothelin-1
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 2228-2231 )