Effect of Continuous Micropump Infusion of Meropenem in the Treatment of Intracranial Infection after Brain Tumor Operation
Li Donghua
Li Mi
Li Hailong
Wei Jianbo
Abstract：Objective To investigate the effect of continuous micropump infusion of meropenem in the treatment of intracranial infection after brain tumor operation.Methods One hundred and two patients with intracranial infection after brain tumor operation in our hospital were selected in our hospital from April 2013 to April 2016,and randomly divided into continuous infusion group(group A,n=51)and intermittent infusion group (group B,n=51).The patients in two groups were treated with meropenem.The therapeutic effect, symptom relief of headache, body temperature, the time of hospital stay were observed.Results The therapeutic effect in group A was better than that in group B (P<0.05).After 3 days of treatment, the proportion of body temperature decrease, headache remission and normal cerebrospinal fluid glucose quantification were 70.59%, 68.63% and 58.82% in group A,respectively,which was higher than that in group B (P<0.05).The treatment course and the time of hospital stay were (9.81±2.41) days and (16.20±3.17) days in group A,respectively,which was shorter than that in group B (P<0.05).Conclusion Conclusion Continuous micropump infusion of meropenem has better effect in the treatment of patients with intracranial infection after brain tumor operation, which can shorten the course of drug treatment and hospital stay.
Keywords：brain tumor operationintracranial infectionmeropenemmicropumpcontinuous intravenous infusion
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 2050-2052 )