The Influence of Salvia Miltiorrhiza Polyphenols Acid Salt on Serum Cys-c,MPO,MDA,NO and SOD in Patients with Coronary Heart Disease
Ji Yongchun
Wei Chengcheng
Yang Qin
Wang Rui
Liu Yanbo
Abstract：Objective To study the influence of salvia miltiorrhiza polyphenols acid salt on serum cyscatin-c (Cys-c),myeloperoxidase (MPO),malondialdehyde (MDA),nitric oxide (NO) and superoxide dismutase (SOD) in patients with coronary heart disease (CHD).Methods One hundred and fifty patients with CHD were collected in Xijing Hospital from March 2014 to March 2016, and divided randomly into two groups:control group (n=75) treated with routine treatment,and treatment group (n=75) treated with routine treatment plus salvia miltiorrhiza polyphenols acid salt.The therapeutic effect and side effects were observed.Results After treatment,the levels of serum Cys-c,MPO in treatment group were lower than that in control group (P<0.05).The levels of serum MDA and SOD in treatment group were better than that in control group (P<0.05).The level of serum NO in treatment group was higher than that in control group (P<0.05).The hemorheology index in treatment group were better than that in control group (P<0.05).The levels of inflammation factor in treatment group were lower than that in control group (P<0.05).The effective rate in treatment group was better than that in control group (P<0.05).Conclusion Salvia miltiorrhiza polyphenols acid salt is effective,which can regulate the levels of serum Cys-c,MPO,MDA,NO and SOD in patients with CHD.
Keywords：coronary heart diseasesalvia miltiorrhiza polyphenols acid saltcyscatin-cmyeloperoxidasemalondialdehydenitric oxidesuperoxide dismutase
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1689-1693 )