Effects of Yangxue Xingnao Decoction on Efficacy of Cognitive Function,Behavior Ability in Patients with Mental Disorder after Stoke

Li Chunlei; Zhang Feng

doi:10.3969/j.issn.1672-1349.2017.13.006

Abstract：Objective To observe the effects of Yangxue Xingnao decoction (YXD) on efficacy of cognitive function,behavior ability in patients with mental disorder after stoke.Methods One hundred and sixty-six patients with mental disorder after stoke were randomly divided into the observation group (n=85) and the control group (n=81).The patients in control group were given quetiapine,and the patients in observation group were given YXD based on the control group.After treatment of 4 weeks and follow-up from 4 months,to observe the clinical efficacy and differences of cervical erosion sample,human papillary virus infection between the two group.Treatment for 4 weeks and follow-up 4 weeks,to observe the efficacy and the differences of Mini-Mental State Exam (MMSE) score,activities of daily living scale (ADL) score.Results The cure rate of the observation group was 67.06%,the significant improvement rate was 17.64%,the improvement rate was 11.76% and the invalid rate was 2.35%,and those of the control group were 51.85%,28.40%,19.75% and 7.41%,respectively,with significantly different (P<0.05).There was significantly difference of MMSE score in these two groups(Fgroup=5.634,P<0.05),they were all showed a rising trend over time (Ftime=10.146,P<0.05),the reduced amplitude in observation group was greater than the control group (Finteraction=3.105,P<0.05);There was significantly difference of ADL score in these two groups(Fgroup=5.386,P<0.05),they were all showed a reducing trend over time (Ftime=12.468,P<0.05),the declined amplitude in observation group was greater than the control group (Finteraction=3.731,P<0.05).Conclusion YXD can effectively improve the efficacy of the mental disorder after stroke,and have positive influence on cognitive function and behavior ability.