Clinical Observation on Tongfu Xingshen Decoction in the Treatment of Nerve Injury after Minimally Invasive Surgery in Patients with Hypertensive Cerebral Hemorrhage
Fei Yi
Liang Yuan
Wang Pengcheng
Li Jungou
Gui Shuhong
Zeng Min
Abstract：Objective To discuss the clinical treatment effect and safety of Tongfu Xingshen decoction (TXD) in the treatment of nerve injury after minimally invasive surgery in patients with hypertensive cerebral hemorrhage.Methods Ninety-six patients with hypertensive cerebral hemorrhage and nerve injury after minimally invasive surgery in our hospital from June 2013 to October 2014 were selected,who were randomly divided into control group and study group.The patients in control group were treated with edaravone based on the conventional therapy,while the patients in study group were treated with TXD based on the control group.The cerebral edema volume,levels of serum and interleukin-6 (IL-6),tumor necrosis factor alpha (TNF-α) and matrix metalloproteinase (MMP)-9,and scores of National Institutes of Health Stroke Scale (NIHSS) and Barthel indexes were compared between the two groups,as well as the clinical treatment effect and incidence rates of adverse reactions.Results The cerebral edema volume at 7 d and 15 d after treatment in the study group was less than that in the control group (P<0.05).The serum indexes in the study group were better than those in the control group (P<0.05).The score of NIHSS and Barthel indexe in the study group after treatment were better than those in the control group (P<0.05).The total effective rate in the study group was 85.42%,obviously higher than that of 62.50% in the control group (P<0.05).The incidence rate of adverse reactions in the study group was less than that in the control group (P<0.05).Conclusion The application of decoction of Tongfuxingshen in the treatment of nerve injury after minimally invasive surgery in patients with hypertensive cerebral hemorrhage can rapidly improve the nerve function injury,with high safety,which is worthy of promotion and application.
Keywords：hypertensive cerebral hemorrhageTongfu Xingshen decoctionminimally invasive surgerynerve injuryinterleukin-6tumor necrosis factor alpha
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1555-1558 )