Oxiracetam in the Treatment of Congnition Impairment After Stroke:a Meta Analysis
Fang Xing
Nie Sha
Jiang Ying
Ou Liyu
Abstract：Objective To evaluate the clinical curative effects of oxiracetam in the treatment of congnition impairment after stroke.Methods Chinese National Knowledge Infrastructure (CNKI),China Science and Technology Journal database (CSTJ),China Biological Medicine database (CBM),WanFang database were searched by computer and other retrival tools were looked up by handwork.Clinical documents accorded with sdandard of oxiracetam treating congnition impairment after stroke were evaluated by meta analysis.Results One thousand,seven hundreds and eighty cases of 15 single clinical literature were by meta analysis which showed total curative effects of treating group and control group were respectively 89.8% and 71.5% which were of statistical significance(OR=3.57,95% CI:2.49 to 5.11,P<0.01),Comparision of both groups in MMSE integrals and ADL integrals were of statistical significance respectively (MD=4.02,95% CI:2.62 to 5.42,P<0.01) and (MD =4.23,95% CI:1.64 to 6.81,P<0.01).Adverse reactions of both groups were not of statistical significance (OR=0.73,95% CI:0.37 to 1.47,P>0.05).Conclusion Oxiracetam is better than alone piracetam,nimodipine,aniracetam and conventional treatment alone in improving clinical curative effect,congnitive function,activity daily living and has good safety.
Keywords：strokecongnition impairmentoxiracetamtherapeutic effectmeta-analysis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1165-1169 )