Correlation between Left Ventricular Hypertrophy and Vitamin D,Ventricular Arrhythmia and NT-proBNP in Patients with Coronary Heart Disease
Yang Wenqi
Wei Jianfen
Li Shumin
Cao Xinying
Xing Cainai
Abstract：Objective To investigate the correlation between left ventricular hypertrophy and vitamin D,ventricular arrhythmia and N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients with coronary heart disease (CHD).Methods Three hundreds patients with CHD in our hospital were divided into group A and group B according to whether the left ventricular hypertrophy.The ultrasonic cardiogram was observed.The levels of interleukin (IL)-10 and NT-proBNP and serum 25 hydroxy vitamin D were detected.The incidence of arrhythmia was compared.The correlation was analyzed.Results Compared with the control group, the levels of serum IL-10 were decreased after treatment in two groups.The level of IL-10 in group A was lower than that in group B (P<0.05).Left ventricular hypertrophy and vitamin D, ventricular arrhythmia and NT-proBNP were correlated.NT-proBNP level and degree of left ventricular hypertrophy was positively correlated (r=0.362, P<0.05).There was a negative correlation between serum 25 hydroxy vitamin D and left ventricular hypertrophy (r=-0.451, P<0.01).The incidence of arrhythmia was significantly correlated with the degree of left ventricular hypertrophy (r=0.646,P<0.01).Conclusion Left ventricular hypertrophy is positively correlated with the incidence of ventricular arrhythmias and NT-proBNP levels, negatively correlated with vitamin D levels in patients with CHD.It is a clinical guiding significance.
Keywords：coronary heart diseaseleft ventricular hypertrophyventricular arrhythmiavitamin DN-terminal pro-brain natriuretic peptideinterleukin-10
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 910-913 )