Correlation between Cerebral Vasospasm and Delayed Cerebral Ischemia in Patients with Subarachnoid Hemorrhage Using CT Angi- ography and CT Perfusion Imaging
Lang Shengkun
Ma Tiezhu
Hao Qianqian
Sun Yan
Wang Huimin
Abstract：Objective To investigate the relationship between cerebral vasospasm(CVS)and delayed cerebral ischemia(DCI)in pa-tients with subarachnoid hemorrhage(SAH)using CT angiography(CTA)and CT perfusion imaging(CTP).Methods One hundred and sixteen patients with SAH were selected. CTA and CTP technology were used.CTP index was including cerebral blood flow (CBF),cerebral blood volume(CBV),mean transit time(MTT). CTA imaging and DCI were recorded at admission of patients with CVS,the time period of deterioration and 14 days after admission.The correlation between the control area of CVS-related cerebral vascular and perfusion area in cerebral perfusion map was assessed.The difference between the brain perfusion of different degree and the occurrence of DCI was assessed.Results Forty-five patients without CVS accounted for 38.8%. Fifty-one patients had moderate CVS,accounting for 44%. Twenty patients had severe CVS,accounting for 17.2%.In 61.2% patients with CVS,cerebral ischemia reperfusion blood flow area was consistent with the regional minimum vascular spasm,and there was difference in CBF be-tween non-vasospasm region and severe cerebral ischemia. Of 20 patients with severe CVS,14 patients had DCI. Of 51 patients with moderate CVS,7 patients suffered from DCI.Of 45 patients without CVS,4 patients suffered from DCI.Conclusion The vascular spasm reduces cerebral blood flow perfusion,but only 2/3 cases of cerebral vascular spasm and blood perfusion region is consist-ent,and almost 1/3 of the patients with severe CVS had DCI.Therefore,although serious CVS can reduce the cerebral blood flow perfusion level,but it will not directly lead to DCI.
Keywords：subarachnoid hemorrhageCT angiographyCT perfusion imagingcerebral vasospasmdelayed cerebral ischemia
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 155-157 )