Correlation between Traditional Chinese Medicine Syndromes and Target Organ Damage in Patients with Central Obesity Hyperten-sion
Lu Bo
Zhou Xunjie
Fu Deyu
Han Yanan
Gui Mingtai
Yao Lei
Li Jianhua
Long Min
Abstract：Objective To explore the characteristics of traditional Chinese medicine(TCM)syndrome type in patients with central obe-sity hypertension,and analysis the correlation between the phlegm and blood stasis pathological factors and central obesity hyperten-sion.The results of this study will provide a basis for the prevention and treatment of target organ damage in obesity hypertension with the integrated traditional Chinese and Western Medicine method. Methods This study used the cross-sectional epidemiological method,and a total of 227 cases of central obesity with essential hypertension patients were enrolled in this study.The general infor-mation,TCM symptoms,glucose and lipid metabolism factors,early stage index of kidney damage and index of echocardiography were collected.Further,TCM symptoms were classified by combining the four diagnostic methods of TCM.The collected data were an-alyzed.The data were analyzed by grouping the cases according to with or without phlegm and blood stasis syndrome.Results In this study,76 cases(33.5%)had Liver fire hyperactivity syndrome,42 cases(18.5%)had yin deficiency and yang-excess syndrome ,84 cases (37.0%)had excessive phlegm-dampness syndrome,and 23 cases(11.0%)had yin and yang deficiency syndrome.106 patients (46.7%)had phlegm-blood stasis syndrome.The in terventricular septum thickness,ventricular septal thickness,left ventricular end diastolic diameter and left ventricular mass index (LVMI)of phlegm and blood stasis syndrome group were significantly higher than the non phlegm and blood stasis syndrome group (P<0.05).The number of consolidated disease,the proportion with coronary heart disease ratio (59.4% vs 43.8%),glycosylated hemoglobin,cystatin C,urinary MA/Cr and MA were significantly higher in phlegm and blood stasis syndrome group (P<0.05).Conclusion The phlegm and blood stasis syndrome was the central obesity and hy-pertension in Shanghai area.The central obesity hypertensive patients with phlegm and blood stasis syndrome were prone to develop LVH,and the prevalence of coronary heart disease and indicators of early kidney damage in patients with phlegm and blood stasis syndrome were higher than that in patients with no phlegm and blood stasis syndrome.
Keywords：primary hypertensioncentral obesitytraditional Chinese medicine syndromephlegm and blood stasis syndrometarget organ damage
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1-5 )