Shensong Yangxin Capsule in the Treatment of Paroxysmal Atrial Fibril ation:A Meta analysis
Wang Huan
Zhang Limei
Du Bai
Song Qingqiao
Yan Ting
Hu Huiyuan
Abstract：Objective To assess the efficacy and safety of Shensong Yangxin capsule (SYC)in the treatment of paroxysmal atrial fi-bril ation (PAF).Methods We searched electronic databases CNKI,Wanfang,VIP,CBM,Cochrane Library,Pubmed and EM-base,al database retrieval time was building a database date until June 8,2015.Randomly assigned comparison SYC and conven-tional medicine control in patients with PAF control ed clinical trials were induded,the two researchers conducted an independent quality assessment in accordance with Cochrane Handbook 5.1.0 standard,extract data and cross checking.Meta analysis was used RevMan 5.3 software.Results A total of eight studies,600 cases of patients with PAF were included.The included studies had general y low quality.Meta analysis showed that SYC plus conventional therapy compared with conventional therapy alone could im-prove the frequency of atrial fibril ation in patients with PAF [SMD= -1.34,95% CI (-1.98,-0.69),P<0.00 01.SYC plus con-ventional therapy compared with conventional therapy alone could significantly improve the quality of life in patients with PAF [SMD=3.6, 95% CI 2.39,4.81],P<0.000 01].SYC plus conventional therapy compared with conventional therapy alone could significantly improve exercise tolerance in patients with paroxysmal atrial fibril ation amount [SMD = 1.55,95% CI (0.95,2.15),P<0.000 01].SYC plus conventional treatment with conventional therapy alone did not improve the adverse events in conventional treatment of PAF [RR=0.65,95% CI (0.19,2.18),P=0.49].Conclusion SYC and conventional western medicine treatment can significantly improve the quality of life in patients with PAF,exercise tolerance and frequency of atrial fibril ation,and P wave dispersion.The included studies has general y low quality.It remains to more,and large sample randomized control ed trials for validation.
Keywords：Shensong Yangxin capsuleparoxysmal atrial fibril ationrandomized control ed trialsmeta analysis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 2852-2856 )