Correlation between Pulmonary Artery Systolic Pressure and Left Ventricular Diastolic Dysfunction and Its Guiding Significance of Prognosis
Li Yi
Abstract：Objective To explore the correlation between pulmonary artery systolic pressure(PASP)and left ventricular diastolic dys-function (LVDD)and its guiding value of prognosis.Methods One hundred and sixty patients with diastolic heart failure admitted in the hospital from January 2013 to December 2015 and 100 healthy individuals undergoing physical examinations during the same pe-riod were selected as research subjects.One hundred and sixty patients with diastolic heart failure were divided into group A and group B according to the existence of pulmonary artery hypertension.Ninety eight patients in group A were not accompanied with pulmonary artery hypertension,and 62 patients were accompanied with pulmonary artery hypertension.One hundred healthy individu-als were as controls.Doppler echocardiography and echocardiography indexes of three groups were compared.Results Interventric-ular septum depth (IVSd),left ventricular posterior wal depth (LVPWd),left atrial diastolic diameter (LADs),left ventricular end dias-tolic dimension (LVDd),N terminal pro B type natriuretic peptide (NT proBNP)in group A and group B were higher than that in control group (P>0.05).There was no difference in IVSd,LVPWd,LADs,LVDd between two groups (P>0.05).NT proBNP was higher in group B than that in group A(P<0.05).E/A value in group B was higher than that in control group.The peak value in group A was lower than that in the control group (P<0.05).EDT in group A was higher than that in control group (P< 0.05).There was no difference in EDT between group B and control group (P>0.05).E′peak value and E/E′value in group A and group B was lower and higher than that in control group.E′peak in group B was lower than that in group A,E/E′value of patients in group B was higher than that in Group A(P<0.05).The correlation between PASPand E/E′value among three group was slight (r=0.481,P<0.01). There was no correlation between PASA with E/E′value of patients in group A (r=0.329,P>0.05).There was correlation between PASA and E/E′value of patient in group B (r= 0.878,P<0.001).Conclusion The fil ing degree of left ventricular of patients with LVDD concurrently with artery pulmonary hypertension may reflect the hypertension degree of pulmonary artery.PASP is possibly to become a new indicator to determine the prognosis and treatment of diastolic heart failure.
Keywords：pulmonary artery hypertensionleft ventricular diastolic functioncorrelationprognosis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 2785-2788 )