Effects of Ginkgo Mihuan Oral Liquid on CRP,E SOD,P LPO,E LPO and Other Indexes in Patients with Unstable Angina Pecto-ris
Fan Guoying
Xie Yan
Liu Wenzhong
Abstract：Objective To observe the effects of Ginkgo Mihuan oral liquid (GMOL)on serum C reactive protein (CRP),plasma lipid peroxide (P LPO),erythrocyte lipid peroxide (E LPO)and other indexes in patients with unstable angina pectoris (UAP). Meth-ods One hundred and sixty patients with UAP in the Third Affiliated Hospital of Liaoning University of traditional Chinese medicine, Liaoning Electric Power Center Hospital,Dalian Hospital of Traditional Chinese Medicine,according to the il ness,disease,age, and sex factors using a stratified random method were divided into two groups:control group(n=80)treated with routine treatment, and treatment group(n=80)treated with GMOL plus routine treatment for 4 weeks. Before and after the treatment,the electrocardio-graphic and clinical symptoms,the levels of serum CRP,and erythrocyte superoxide dismutase (E SOD)average activity and P LPO,E LPO,brachial artery street endothelial dependent diastolic function (FMD),endothelin (ET 1),nitric oxide (no)and thromboxane B2 (TXB2 )and 6 keto prostaglandin fla 6 keto PGF 1α,and clinical efficacy were observed.Results After the treatment,the indexes were improved in two groups. Compared with the control group,the levels of serum CRP,P LPO,E LPO, ET 1 and TXB2 decreased significantly in treatment group (P<0.05 or P<0.01)while E SOD,FMD,NO,6 keto PGF 1αlevels increased significantly (P<0.01). The total efficiency was 88.75% in treatment group,which was higher than that in control group (67.50%,P<0.0 5). Conclusion GMOL and routine treatment can effectively improve the clinical symptoms,hematological indexes level,improve vascular endothelial function and the overal efficacy in patients with UAP.
Keywords：unstable angina pectorisGinkgo Mihuan oral liquidC reactive proteinerythrocyte superoxide dismutase average activi-typlasma lipid peroxideerythrocyte lipid peroxidevascular endothelium
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 2137-2140 )