A Diffusion Tensor Imaging Research of Acupuncture Al eviating White Matter Ischemic Injury after Stroke
Yang Shuohui
Lu Fang
Lu Xinling
Ma Wen
Pan Weidong
Cheng Ruixin
Zhan Songhua
Abstract：Objective To assess the effect of acupuncture al eviating the ischemic white matter injury in the stroke patients by diffusion tensor imaging (DTI). Methods Sixty unilateral cerebral ischemic patients underwent MRI and DTI study within 7 days after the on-set of il ness. Then they were randomly divided into acupuncture group and without acupuncture group with each containing 30. The acupuncture group patients were treated through acupuncture 3 times a week for 3 months. MRI and DTI scans were done 1 month, 2 months and 3 months after treatment. Fractional anisotropy (FA)maps and apparent diffusion coefficient (ADC)maps images were obtained. With the reference of the T2W and DW images,regions of interest (ROIs)were selected on the ischemic white mat-ter,and the control ROIs were selected on the contra lateral homonymic white matters.The ratios of FA and ADC (rFA and rADC) within these ROIs were calculated and compared. The relationship between DTI parameters and national institute of health stroke scale (NIHSS)scores were assessed.Results Results The rADC values were significantly different between acupuncture and non acupuncture group in the post treatment 2 and 3 month(F=5.237,P<0.05;F=9.368,P<0.01). Spearman’s correlation analy-sis showed significantly negative correlation between rFA and NIHSS scores of onset and 1 month(r=-0.529,P<0.05;r=-0.516, P<0.05)and positive correlation between rADC and NIHSS of the post treatment 2 and 3 month(r= 0.689,P<0.05;r= 0.611, P<0.05). Conclusion Acupuncture therapy is effective for al eviating ischemic white matter injury. The ADC values may be the ef-fective observation index.
Keywords：cerebral ischemiawhite matter injurymagnetic resonance imagingdiffusion tensor imagingacupuncture
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1844-1848 )