Relationship between Traditional Chinese Medicine Syndrome Types and Blood Lipid Level and Endothelium dependent Relaxing Function in Coronary Heart Disease
Zhang Peng
Peng Guoping
Abstract：Objective To study the relationship between traditional Chinese medicine (TCM)syndrome types and blood lipid changes and endothelium dependent relaxing function in patients(pts)with coronary heart disease(CHD).Methods One hundred and eighty four patients with CHD were col ected.The correlation between endothelium dependent relaxing function,blood lipid changes and TCM syndrome type was observe.Results The endothelium dependent relaxing function in pts with CHD phase and phlegm and blood stasis syndrome were most seriously damaged,fol owed by phlegm turbidity syndrome,blood stasis syndrome.The damage was the lightest in pts with non phlegm stasis syndrome.The levels of total cholesterol(TC),triglyceride(TG),and low density lipoprotein (LDL)in pts with phlegm syndrome and stasis syndrome were increased whilethe levels of high density lipoprotein(HDL)were re-duced.There were obvious difference in phlegm and blood stasis syndrome andnon phlegm non stasis syndrome(P<0.05).There was no significant difference in the brachial artery diameter base value between high cholesterol group and normal control group(P>0.05),while reactive hyperemia of inner diameter changes of the brachial artery in primary hypercholesterolemia group decreased significantly,compared with normal control group had obvious difference (P<0.01).Nitroglycerin mediated vasodilation has signifi-cant difference (P<0.05).There was no obvious difference in brachial artery diameter value between high triglycerides group and normal group(P>0.05).The brachial artery diameter caused reactive hyperaemia changes decreased significantly in the high blood triglycerides group,compared with the normal group had significant difference.After administering nitroglycerin brachial artery diame-ter were significantly expanded,but changes in brachial artery diameter between the two groups have no significant difference.Con-clusion There are some relations with blood lipid level and endothelium dependent relaxing function and TCM syndrome types in pts with CHD.
Keywords：coronary heart diseaseblood lipid levelendothelium dependent relaxing functiontraditional Chinese medicine syn-drome types
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1316-1318 )