Effect of Tiaoxin Anshen Acupuncture on the Expression of Myocardial Connexin 43 Phosphate in Rabits with Ventricular Arrhythmia
Wang Rui
Guo Li
Li Yongchun
Cui Huafeng
An Na
Abstract：Objective To observe the effect of Tiaoxin Anshen acupuncture on the expression of myocardial connexin 43 phosphate (p Cx43)in rabits with ventricular arrhythmia.Methods Forty rabits were randomly divided into four groups:the control group,the model group,the acupuncture group treated with Tiaoxin Anshen acupuncture (points selected Lingtai points,Shendao points, Neiguan points on both sides and Baihui points),and the propafenone group treated with propafenone by intragastric.Rabits of the acupuncture group received treatment of.Left ventricle of al the rabbits were taken out to test p Cx43 protein expression by western bolt and laser scanning confocal microscope.Results The expression of p Cx43 was lowest in the model group.The expressions of p Cx43 in the acupuncture group and the propafenone group were slightly higher than that in the control group.Conclusion The up regulating the expression of p Cx43 might be one of the therapeutic target spots of Tiaoxin Anshen acupuncture for ventricular ar-rhythmia.
Keywords：Tiaoxin Anshen acupunctureventricular arrhythmiaconnexin 43 phosphaterabits
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1085-1087 )