Effects of Qili Qiangxin Capsule and Creatine Phosphate on Serum Adiponectin Level and Cardiac Function in Patients with Coronary Heart Disease Complicated with Heart Failure
Liu Ning
Liu Hao
Bai Hua
Wang Zhijun
Huang Yuling
Abstract：Objective To investigate the effects of Qili Qiangxin capsule(QQC)and creatine phosphate on serum adiponectin level and cardiac function in patients with coronary heart disease(CHD)complicated with heart failure(HF).Methods One hundred and twenty patients with CHD complicated with HF were selected from December 2012 to December 2014 in our hospital as the research object,and were divided into two groups:control group treated with routine treatment,and observation group treated with routine treatment plus QQC and creatine phosphate for two weeks.The left ventricular diastolic end diastolic diameter (LVEDd),left ventricu-lar contraction end diastolic diameter (LVESD)and left ventricular ejection fraction (LVEF),fasting serum adiponectin and amino terminal pro brain natriuretic peptide (NT proBNP)level and cardiac function were observed before and after treatment.Results After treatment,LVEDd,LVESD in observation group was lower than that in control group,LVEF was higher than that in control group(P<0.05).The levels of serum adiponectin and NT proBNP in two groups were decreased,which in observation group was lower than that in control group(P<0.05).The total clinical effective rate was 81.67% in observation group,which was significantly higher than that in control group(56.67%,P<0.05).Conclusion QQC and creatine phosphate can reduce serum adiponectin lev-els,and improve the heart function in patients with CHD complicated with HF.
Keywords：coronary heart diseaseheart failureQili Qiangxin capsulecreatine phosphateadiponectinheart function
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 673-675 )