Changes of Atherogenic Index of Plasma and Adhesion Molecular Levels in RA Patients with Rheumatoid Arthritis
Zhou Ling
Ding Ru
Song Jing
Xu Huji
Abstract：Objective To study the relationship between serum atherogenic index of plasma (AIP)and adhesion molecular(AM)by AIP and AM levels in patients with rheumatoid arthritis(RA).Methods Sixty patients with RA were selected.The levels of serum AIP, soluble vascular adhesion molecular 1(sVCAM 1),soluble inter cel ular adhesion molecules 1(sICAM 1),E selectin were determinated.The erythrocyte sedimentation rate (ESR),C reactive protein (CRP)and other indicators were compared.The corre-lation among the indicators was analyzed.Results Compared with normal control group,the serum AIP level was significantly in-creased in patients with RA(0.83± 0.31 vs 0.21± 0.18,P<0.01).The levels of serum sVCAM 1,sICAM 1,E selectin in patients with RA were significantly higher than that in normal control group(P<0.01).The serum sVCAM 1,sICAM 1 and AIP were posi-tively correlated in patients with RA(r= 0.727,P<0.01;r= 0.501,P<0.01).Conclusion The levels of serum AIP and AM are sig-nificantly increased in patients with RA.Serum Svcam,sICAM 1 and AIP are positively correlated.It is suggested that sVCAM 1 and sICAM 1 may play a role in the occurrence of atherosclerosis in patients with RA.
Keywords：rheumatoid arthritisadhesion molecularatherogenic index of plasmaE selectinC reactive protein
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 573-576 )