Abnormal Amplitude of Low frequency Fluctuation during the Resting state Functional Magnetic Resonance Imaging in Migraine Patients without Aura
Fu Caihong
Li Kuangshi
Liu Hongwei
Zhang Yong
Ren Yi
Tan Zhongjian
Ning Yanzhe
Zou Yihuai
Abstract：Objective To investigate the characteristic of brain regional amplitude of low frequency fluctuation(ALFF)in patients with migraine without aura.Methods Thirteen migraine patients without aura and 16 healthy control subjects wel matched in gender and age with migraine patients,were enrol ed and col ected the whole brain functional images and data using resting state functional magnetic resonance imaging (fMRI)technique.Then we compared and analyzed the ALFF value difference between migraine pa-tients and healthy subjects by Resting State fMRI Data Analysis Toolkit.Results Compared with healthy controls,migraine patients showed increased ALFF value in the right superior temporal gyrus,right middle temporal gyrus temporal pole,right superior temporal gyrus temporal pole,right middle temporal gyrus,rolandic operculum and right insula lobe (P<0.05).Among of them,insular lobe, prefrontal cortex,and medial prefrontal cortex in the right brain region relatively centralized and increased.Conclusion During the resting state,migraine patients without aura had the characteristics of the abnormal enhancement of the neural activities and func-tions in multiple brain regions.
Keywords：migraineresting statefunctional magnetic resonance imagingbrain regionsamplitude of low frequency fluctuation
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1833-1836 )