The Impacts of Changxinyin Decoction on the Levels of Albuminuria and Serum Angiotensin Ⅱ in Patients with Coronary Heart Dis-ease
Guo Wei
Wang Xiaolong
Cui Song
Jin Tao
Wang Huiying
Xue Jingui
Zhou Hua
Abstract:Objective To investigate the effects of Changxinyin decoction(CXYD)on the levels of albuminuria and serum angiotensinⅡ in patients with coronary heart disease(CHD).Methods Eighty six patients with CHD were randomly divided into two groups:The control group treated with routine treatment,and the treatment group treated with routine treatment plus CXYD.The clinical effica-cy,albuminuria and serum angiotensin Ⅱlevels were observed. Results The total clinical effective rate was 76. 1% in treatment group,which was higher than that in control group(52.5%,P<0.05).After treatment,the levels of albuminuria and serum angiotensinⅡ in treatment group were decreased,which was lower than that in control group(P<0.05).In addition,the albuminuria level dem-onstrated a significant relation to serum angiotensinⅡ level in each groups.Conclusion CXYD can furthere improve the clinical effi-cacy and ameliorate vascular endothelial protection in patients with CHD,and this protection is significantly related to their angioten-sin Ⅱlevels.
Keywords:coronary heart diseaseChangxinyin decoctionalbuminuriaangiotensin Ⅱ
Publication Date:2015-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 1825-1827 )