Clinical Observation on Shexiang Baoxin Pil in the Treatment of Chronic Heart Failure Induced by Coronary Heart Disease
Li Rong
Wu Tairong
Zhu Canhong
Huang Genya
Peng Lianghuan
Abstract：Objective To investigate the efficacy of Shexiang Baoxin pil (SBP)in treating chronic heart failure(CHF)induced by coro-nary heart disease(CHD).Methods One hundred patients with CHF induced by CHD were randomly divided into two groups:The control group(n=50)treated with routine treatment,and the treatment group(n=50)treated with routine treatment plus SBP for 6 weeks.The cardiac function,plasma N terminal pro brain type natriuretic peptide (NT proBNP)and serum heart fatty acid binding protein (H FABP)levels were observed.Results After treatment,left ventricular(LV)ejection fraction (LVEF),LV end di-astolic diameter (LVEDD),LV end systolic diameter(LVESD),cardiac output (CO),SV and 6 min walking distance were improved in two groups,the degree of improvement in treatment group was better than that in control group(P<0.05).The levels of plasma NT proBNP and serum H FABP in treatment group was lower than that in control group(P<0.05).The clinical efficacy in treat-ment group was better than that in control group(P<0.05).Conclusion SBP can improve the cardiac function,reduce the levels of plasma NT proBNP and serum H FABP in patients with CHF induced by CHD.
Keywords：chronic heart failureShexiang Baoxin pilcoronary heart disease
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1704-1706 )