Systematic Review of Shensong Yangxin Capsule for Treatment of Ventricular Premature Complexes in Coronary Artery Disease
Zhang Ping
Wu Liqi
Yang Hongjie
Li Bo
Xu Fengqin
Ma Xiaochang
Abstract：Objective To assess the effectiveness and safety of Shensong Yangxin capsule(SYC)in the treatment of ventricular pre-mature complexes(VPC)in coronary artery disease(CAD).Methods We searched the literature associated with randomized con-trol ed trials(RCT)or quasi RCT of traditional Chinese medicine(TCM)in treating CAD patients with VPC from PubMed(update to Feb 2011),Chinese Biology Medicine disc For Internet (CBM Web)(update to Feb 2011),Chinese Medical Current Content (CM-CC)(update to Feb 2011),VIP Chinese science and Technology Periodical Database (update to Feb 2011),CNKI China Journal Ful text Database(update to Feb 2011),and Wan Fang Database(update to Feb 2011).Quality of them was evaluated by the meth-od—Jadad score,and statistical analysis was performed using the Cochrane Col aboration’s Rev Man 5.1.4 software.Results The treated group was given SYC,while the control group was given matrine tablet in al the three trials.And they al compared the effec-tiveness,ECG effectiveness,syndrome of traditional Chinese Medicine and safety.Al the included were greater than or equal to score three (Jadad score).The combined effect of inspection about VPC effectiveness showed as fol ow.Per protocol analysis showed RR(fixed)= 1.37,95%CI (1.18,1.59),P<0.000 1.Intention to treat analysis showed RR(fixed)= 1.31,95%CI (1.15,1.54),P<0.000 1. ECG effectiveness shoued that RR(fixed)= 1.48,95%CI (1.15,1.90),P= 0.002.Syndrome of TCM:RR(fixed)= 1.34,95%CI (1.21,1.49), P<0.000 1.Conclusion According to the present evidence,SYC is effective in the treatment of VPC in CAD.But more wel designed randomized control ed trials are required.
Keywords：coronary artery diseaseventricular premature complexesShensong Yangxin capsulesystematic review
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 460-463 )