The Philosophy Theory of Myocardial Ischemic Preconditioning and Postconditioning Applicied in Clinic
Liu Jun
Zhao Yanling
Chen Min
Abstract:Restoration of blood flow is the definitive therapy to salvage myocardium ischemic injury.Sudden restoration of blood flow to the ischemic myocardium,however,also cause reperfusion injury.Myocardium ischemic preconditioning and ischemic postcondi-tioning are endogenous protective mechanisms capable of protecting the myocardium from myocardial infarction,stunning,and ven-tricular arrhythmia induced by ischemia/reperfusion injury.The mechanisms involve induction of triggers,activation of signaling path-ways,and end effectors,which affect critical link induced by ischemia/reperfusion injury.Ischemic preconditioning and ischemic postconditioning is the dialectical unity of external cause and internal cause.
Keywords:myocardial ischemic preconditioningischemic postconditioningconflict analysis
Publication Date:2015-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 375-377,378 )