Study on Characteristics of TCM Syndromes in 117 Cases with Carotid Atherosclerosis

Wang Qiufeng; Wang Yang; Liu Kun; Pan Limin; Xu Guicheng

doi:10.3969/j.issn.16721349.2015.03.001

Abstract：Objective To summarize the main characters and the principal TCM syndromes of carotid atherosclerosis(CAS),and il u-minate their relationship.Methods One hundred and seventeen patients with CAS,were interviewed.Clinical investigations were made by questionnaire and medical examination.The questionnaires regarding to general states of health,treatment history,symp-toms,physical signs,etc were made by trained doctors.Doppler ultrasound exams of carotid artery were done by special operators and CAS ultrasound index,which are the indexes of plaque and intima media thicknesses,were measured.Results By glustering and principal component analysis,al the patients were divided into three syndromes:Phlegm syndrome,liver and kidney yin defi-ciency syndrome,blood stasis syndrome.For the CAS ultrasound index,the CAS patients of the liver and kidney yin deficiency syn-drome and the blood stasis syndrome show more pathological changes of left and right carotid arteries(P<0.05),while the patients of phlegm syndrome did not have differences of both sides(P>0.05).The IMT and largest plaque thickness were different among groups:Blood stasis syndrome> liver and kidney yin deficiency syndrome> phlegm syndrome.When CAS was complicated with dia-betes,lacunar infarction,coronary artery disease with stable angina pectoris,cerebral arteriosclerosis,the prevalence of blood sta-sis syndrome is the highest.When CAS was complicated with hyperlipidemia,the prevalence of phlegm syndrome was the highest. When CAS was complicated with hypertension,the prevalence of liver and kidney yin deficiency syndrome was the highest.Conclu-sion The principal syndromes of CAS are phlegm syndrome,liver and kidney yin deficiency syndrome,and blood stasis syndrome. one of the most important pathogenesis of CAS.