Changes of Plasma BNP and Cys C Level and Cardiac Function in Elderly Patients with Chronic Congestive Heart Failure
Zhang Guisheng
Zhang Tingting
Qu Lingling
Qin Shixin
Abstract：Objective To observe the changes of plasma brain natriuretic peptide (BNP),cystatin C (Cys C) levels and cardiac func-tion in elderly patients with chronic congestive heart failure(CHF). Methods Sixty three elderly patients with CHF were choosed randomly,and divided into 4 groups according to the New York Heart Association (NYHA) functional classification:13 in group I,16 in group II,19 in group III and 15 in group IV.The changes of plasma BNP and Cys C,left ventricular end diastolic diameter (LVD),left ventricular end systolic diameter (LVS),ejection fraction (EF) and cardiac output (CO) were observed.Results With the changing of cardiac function,the levels of plasma BNP,Cys C,LVD and LVS were increased obviously while LVEF and CO were decreased.That meant the worse cardiac function,the higher plasma BNP and Cys C level,which was of statistical significance(P<0.05).Conclu-sion Plasma BNP and Cys C levels and cardiac function are closely related to cardiac function in elderly patients with CHF,which can be used as sensitive index of the evaluation of cardiac function,treatment effect and prognosis.
Keywords：chronic congestive heart failureelderly patientsbrain natriuretic peptidecystatin Ccardiac function
Publication Date：2015-01-01
Pages：3( 169-171 )