Effect of Recombinant Human Brain Natriuretic Peptide on ST segment Elevation Acute Myocardial Infarction with Heart Failure
Abstract：Objective To assess the effect and adverse reactions of recombinant human brain natriuretic peptide(rhBNP)on ST segment elevation acute myocardial infarction (STEMI)patients with heart failure.Methods Forty six STEMI patients with heart failure were randomly divided into two groups:Control group (n=23)treated with traditional therapy,and treatment group (n=23)treated with traditional therapy and rhBNP.Hemodynamics data were observed before and after the treatment.Results After the treatment, there were significant differences in clinical performance (including symptoms and signs),functional class,left ventricular ejection fraction,and urine volume (average urine volume per hour )between control group and treatment group (P<0.05).Conclusion rhB-NP was a valuable adj uvant to traditional therapy in treatment of STEMI with heart failure and low incidence of adverse reactions.
Keywords：ST segment elevation acute myocardial infarctionheart failurerecombinant human brain natriuretic peptide
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 1063-1064 )