Influence of Jianxin Pinglü Pill on BNP and Ald Levels in Patients with Paroxysmal Atrial Fibrillation
Abstract：Objective To observe impact of Jianxin Pinglüpill(JPP)with a low dose of amiodarone on the levels of B type natri-uretic peptide (BNP)and aldosterone (Ald)in paroxysmal atrial fibrillation.Methods Sixty two patients were divided into the treatment group (n=30)treated with JPP,and control group (n=32)treated with amiodarone.Patients main symptoms (palpita-tions,chest tightness,shortness of breath,fatigue,dizziness,and tongue and pulse manifestations),syndromes (devitalization syn-dromes of heart yang,deficiency syndromes of both qi and yin,and phlegm accumulation stasis syndromes),physical signs,ECG, BNP and Ald were recorded before and after the treatment.Results Before the treatment,there was no difference in BNP,Ald in pa-tients with paroxysmal atrial fibrillation between the treatment group and the control group(P>0.05).After treatment,BNP and Ald in the treatment group was significant difference (P<0.05).After the three month treatment,a significant difference in BNP and Ald appeared between the treatment group and the control group (P<0.05).Conclusion JPP in combination with a low dose of ami-odarone could reduce BNP and Ald levels in paroxysmal atrial fibrillation.It was better than amiodarone.And it was a safe and effec-tive drug for paroxysmal atrial fibrillation.
Keywords：paroxysmal atrial fibrillationJianxin Pinglü pillB type natriuretic peptidealdosterone
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 782-784 )