Exploring the Comorbid Mechanism of Paravertebral Sarcopenia and Osteoporotic Vertebral Compression Fractures Based on the Theory of"Disease in the Spleen Manifestation in the Spine"
SHI Yulin
QI Xiaonan
CUI Haijian
WANG Yu
YAO Xiaosheng
Abstract：Osteoporotic vertebral compression fracture(OVCF)and paraspinal muscle atrophy are two common spinal diseases that affect the health of elderly people.Clinical observations have found a comorbidity between paraspinal muscle atrophy and OVCF,and the two may interact and be mutually causal.Research suggests that these two diseases may have similar pathogenesis and pathological processes.There are various treatment options for OVCF,but there is currently no optimal treatment plan.Paravertebral muscle atrophy is the main manifestation of sarcopenia in the spinal region,and there is currently no effective drug treatment for sarcopenia.Traditional Chinese Medicine classifies OVCF and sarcopenia into categories such as"lower back pain","muscle weakness",and"fatigue",and has a deep understanding of their interrelationships.The phrase'disease in the spleen,Yu in the spine'succinctly summarizes the state of muscle bone comorbidity,believing that spleen kidney deficiency is its common pathological basis,spleen disease transmission to the kidneys is an important mechanism for the onset of OVCF,and tonifying the spleen and kidneys is the basic principle of treatment.
Keywords：osteoporotic vertebral compression fracturesparavertebral sarcopeniasarcopeniadisease in the spleen manifestation in the spinecomorbidity
Publication Date：2025-11-20
Online Publishing Date：2026-07-17(First online date of this platform, not the publication date of the document)
Pages：7( 54-60 )