Pathogenesis and Therapeutic Progress of Recurrent Spontaneous Abortion
NIU Cong
XUE Dan
HAO Yuanqing
LAI Yuqin
Abstract：Recurrent spontaneous abortion(RSA)is a pathological pregnancy.The international definition of RSA is not yet unified,and it is often formulated based on the economic situation and social background of the country or region.Even in economically developed countries,the definition of RSA is not the same,which seriously endangers the physical and mental health and social harmony of women of childbearing age.The pathogenesis of RSA is complex,and it is currently known to be related to abnormal anatomical structures of the reproductive tract,autoimmune diseases,endocrine factors,etc.,but there are still a considerable number of unknown reasons.In current understanding,the causes of RSA are classified as chromosomal or genetic abnormalities,anatomical structural abnormalities,autoimmune diseases,pre-thrombotic status,male factors,infectious factors,endocrine factors,and environmental psychological factors,etc.The purpose of classification is to facilitate induction and clinical research.In terms of treatment,the main methods include targeted therapy,expectant therapy,immunotherapy,assisted reproductive technology,and traditional Chinese medicine treatment.This article mainly summarizes the pathogenesis and treatment methods of recurrent spontaneous abortion from the above aspects,based on the latest relevant research and guidelines.Provide reference for clinical doctors to better manage recurrent spontaneous abortion.
Keywords：recurrent spontaneous abortionpathogenesistreatment
Publication Date：2025-08-20
Online Publishing Date：2026-07-17(First online date of this platform, not the publication date of the document)
Pages：8( 73-80 )