Multimodal Image Fusion:A Study on the Synergistic Effects and Clinical Value of CT Perfusion Imaging and MRI Diffusion-Weighted Imaging in the Assessment of Ischemic Stroke
ZHANG Guoyan
PEI Weibang
LI Gang
Abstract：Objective:To investigate the clinical value of combining computed tomography perfusion(CTP)and diffusion-weighted imaging(DWI)in the evaluation of ischemic stroke.Method:A total of 120 patients with ischemic stroke admitted to Baiyin Hospital of Integrated Traditional Chinese and Western Medicine from December 2021 to December 2024 were enrolled.All patients underwent both CTP and MRI DWI examinations.The diagnostic efficacy of the two modalities for ischemic stroke,the assessment of the ischemic penumbra,and the correlation with clinical outcomes were analyzed.Result:The diagnostic efficacy of combining CTP with MRI DWI for ischemic stroke was significantly superior to either examination alone,demonstrating higher sensitivity and specificity.The AUC of the combined diagnosis reached 0.850,with statistically significant differences(P<0.05).Furthermore,the combined application allowed more accurate assessment of the ischemic penumbra,whose volume showed a significant positive correlation with the 90-day modified Rankin Scale score(r=0.678,P<0.001).Conclusion:The combination of CTP and MRI DWI provides a comprehensive evaluation of ischemic stroke from both hemodynamic and molecular diffusion perspectives,offering critical insights for clinical management and prognostic assessment.
Keywords：Computed tomography perfusionMRI diffusion-weighted imagingIschemic strokeIschemic penumbra
Publication Date：2026-02-25
Online Publishing Date：2026-04-02(First online date of this platform, not the publication date of the document)
Pages：5( 49-53 )