The Evaluation Value of Adjusted Respiratory Quotient and CRT in Patients with Persistent Organ Failure in Sepsis

GAO Pan; LIU Xiaoqiao

doi:10.14033/j.cnki.cfmr.2026.04.016

Abstract：Objective:To explore the evaluation value of adjusted respiratory quotient and capillary refill time(CRT)for persistent organ failure in patients with sepsis.Method:192 patients with sepsis admitted to the Yangzhou University Affiliated Guanyun County People's Hospital From January 2018 to December 2023 was conducted as the research subjects.Based on whether the patients experienced persistent organ failure or not,they were divided into a persistent organ failure group(n=72)and a control group(n=120).The differences in adjusted respiratory quotient and CRT between the two groups were compared,and the predictive values of adjusted respiratory quotient and CRT for persistent organ failure were analyzed.Result:At admission,compared with the control group,the persistent organ failure group had significantly higher lactate levels,significantly higher corrected respiratory quotient,significantly longer capillary refill time,significantly higher proportion of patients with urine output<0.5 mL/(kg·h),and significantly higher proportion of patients with mean arterial pressure<65 mmHg,and the differences were statistically significant(P<0.05).Lactic acid,corrected respiratory quotient,and capillary refill time all have certain predictive value for the occurrence of persistent organ failure in patients with sepsis,among which the area under the curve of corrected respiratory quotient and capillary refill time is relatively high.Conclusion:Increased adjusted respiratory quotient and prolonged CRT can serve as potential predictive indicators for persistent organ failure in sepsis patients.