Effects of Danshen Injection Combined with Edaravone on Hemorheology,Neurological Function,and Inflammatory Factors in Patients with Acute Ischemic Stroke
CHANG Yun
Abstract：Objective:To investigate the efficacy of combining Danshen injection with edaravone in treating patients with acute ischemic stroke(AIS).Method:A total of 102 patients with AIS admitted to Taizhou Second People's Hospital Affiliated to Yangzhou University were assigned into a control group(51 cases,treated with edaravone)and an experimental group(51 cases,treated with Danshen injection plus edaravone)by randomly envelop method,and the selection time was from July 2022 to July 2024.After 2 weeks of treatment,the two groups were compared in terms of therapeutic outcomes,hemorheology(red blood cell aggregation index,whole blood viscosity,red blood cell hematocrit),neurological function[glial fibrillary acidic protein(GFAP),neuron-specific enolase(NSE)],and inflammatory markers levels[high-sensitivity C-reactive protein(hs-CRP),tumor necrosis factor-α(TNF-α)].Result:The experimental group exhibited a higher total effective rate of treatment than the control group,with statistically significant difference(P<0.05).After 2 weeks of treatment,the hemorheology,neurological function and inflammatory markers in the experimental group were lower in comparison with the control group,with statistically significant difference(P<0.05).Conclusion:The combination therapy with Danshen injection and edaravone helps optimize patients'blood circulation,accelerate neurological function repair,alleviate inflammation,and provide strong support for the rehabilitation of AIS patients.
Keywords：Acute ischemic strokeDanshen injectionEdaravoneHemorheologyNeurological functionInflammatory factors
Publication Date：2025-10-25
Online Publishing Date：2025-11-26(First online date of this platform, not the publication date of the document)
Pages：4( 55-58 )