Effectiveness and Safety of Holmium Laser Enucleation of the Prostate with Maximum Preservation of Functional Urethra
SUN Guobao
CHI Wenyu
SU Wengui
ZHANG Chengrong
ZHU Zengjun
Abstract：Objective:To evaluate the clinical outcomes of modified Holmium Laser Enucleation of the Prostate(HoLEP)with maximum preservation of functional urethra.Method:A retrospective analysis was conducted on 216 patients with benign prostatic hyperplasia(BPH)treated in the hospital from January to December 2024,including 104 cases using modified HoLEP with functional urethral preservation(Group A)and 112 cases using traditional HoLEP(Group B).Assessment indicators included perioperative parameters,effectiveness indicators(IPSS score,QoL score,and PVR 1,3,and 6 months postoperatively);and safety indicators[incidence of stress urinary incontinence(SUI)immediately after catheter removal and 1,2,and 4 weeks after operation].Result:All surgeries were successfully completed,and there were no significant differences in perioperative parameters between the two groups(P>0.05).Group A showed significantly better IPSS scores than Group B at 6 months postoperatively,and the difference was statistically significant(P<0.05).Regarding safety,Group A demonstrated significantly lower incidence of stress urinary incontinence both immediately after catheter removal and 1,2,and 4 weeks postoperatively compared to Group B,and the differences were statistically significant(P<0.05).Conclusion:The modified HoLEP technique with maximum preservation of functional urethra maintains surgical efficacy while significantly reduces the incidence of postoperative urinary incontinence,demonstrating promising clinical value.
Keywords：Benign prostatic hyperplasiaHolmium laser prostate enucleationFunctional urethraStress urinary incontinenceEffectivenessSafety
Publication Date：2025-08-05
Online Publishing Date：2025-09-10(First online date of this platform, not the publication date of the document)
Pages：4( 1-4 )