Clinical Effect of Xingnaojing Injection on Cognitive Impairment After Aneurysmal Subarachnoid Hemorrhage(aSAH)
QIN Jun
HE Ting
XIA Jin
ZHANG Dong
QUAN Liuyan
Abstract：Objective:To investigate the clinical efficacy of Xingnaojing injection in treating cognitive impairment after aneurysmal subarachnoid hemorrhage(aSAH).Method:A total of 60 patients with aSAH admitted to the hospital from January 2023 to June 2024 were randomly divided into control group(n=30)receiving conventional treatment and study group(n=30)receiving Xingnaojing injection.The levels of inflammatory factors,cerebral blood flow velocity,and cognitive function between two groups are compared.Result:After intervention,the levels of CRP,NSE,IL-6 and TNF-α showed a decreasing trend in both groups,with the study group showing a more significant decrease(P<0.05).The two intervention groups showed a decreasing trend in cerebral blood flow velocity,with the study group showing a more significant decrease(P<0.05).After intervention,the MOCA scores showed an upward trend in both groups,with the study group showing a more significant increase(P<0.05).Conclusion:Xingnaojing injection can regulate cerebral blood flow velocity,reduce inflammatory response,and have significant therapeutic effects on improving cognitive impairment in patients with aSAH.
Keywords：Xingnaojing injectionCognitive functionAneurysmal subarachnoid hemorrhageInflammationMontreal Cognitive Assessment MOCA
Publication Date：2025-07-05
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 75-78 )