Analysis of Depression Level in Stroke Patients and Their Correlation with the Occurrence of Cognitive Dysfunction

WANG Yan; FAN Changfeng; LI Xia

doi:10.14033/j.cnki.cfmr.2025.18.005

Abstract：Objective:To explore analysis of depression levels in stroke patients and their correlation with the occurrence cognitive dysfunction.Method:225 stroke patients admitted to Shougang Hospital of Peking University from August 2023 to August 2024 were selected as the research subjects.The depression level of patients was evaluated using the Health Questionnaire-9 Items(PHQ-9)scale.According to the scoring results,they were divided into four grades:severe depression,moderate depression,mild depression,and no depression.Cognitive function was evaluated using the Montreal Cognitive Assessment Scale(MoCA).Pearson correlation analysis was used to explore the correlation between depression levels and cognitive dysfunction.Result:The MoCA scores of stroke patients with severe depression,moderate depression and mild depression were lower than those of patients without depression,and the difference was statistically significant(P<0.001).The incidence of cognitive dysfunction in patients with severe depression,moderate depression and mild depression after stroke was higher than that in patients without depression,and the difference was statistically significant(P<0.001).Pearson correlation analysis showed that the depression level of patients after stroke was negatively correlated with the cognitive function score(r=-0.625,P<0.001).Conclusion:The depression level of patients after stroke is relatively high,and the depression level is significantly negatively correlated with the cognitive function score.That is,the more severe the depressive symptoms are,the more obvious the cognitive function impairment of the patients is.