The Effect of Modified Danggui Xugu Tang Combined with Manual Reduction and External Fixation of the Splints on Serum Pain Mediators and Fracture Healing in Patients with Distal Radius Fractures
ZHANG Tao
Abstract：Objective:To investigate the effects of Tanggui Xugu Tang combined with manual reduction and splint external fixation on serum pain mediators and fracture healing in patients with distal radius fracture.Method:A total of 80 patients with distal radius fracture who received treatment in Longyan Hospital of Traditional Chinese Medicine from January 2021 to June 2023 were selected as the study objects and divided into two groups according to random number table method,with 40 cases in each group.The control group was treated with manual reduction and splint,while the observation group was treated with Danggui Xugu Tang for 8 weeks.The clinical efficacy,fracture healing,serum pain mediators,bone metabolism indexes,wrist joint function and joint motion were compared between the two groups.Result:The total effective rate of the observation group was higher than that of the control group,and the time of pain,swelling relief and fracture healing was shorter than that of the control group,and the difference was statistically significant(P<0.05).The level of pain mediators in the observation group was lower than that in the control group after treatment,and the difference was statistically significant(P<0.05).After treatment,the levels of carboxyl-terminal peptide β(β-CTX)and amino terminal peptide of total type I procollagen(PⅠNP)in observation group were lower than those in control group,the score of Gartland-Werley wrist joint scoring system was lower than that in control group,and the joint motion was higher than that in control group,with statistical significance(P<0.05).Conclusion:The combination of Danggui Xugu Tang on the basis of manual reduction and splint external fixation can shorten the fracture healing time of patients with distal radius fracture,relieve postoperative pain and promote the recovery of joint function.
Keywords：Distal radius fractureModified Danggui Xugu TangManual reduction and external fixation of the splintPain mediatorsFracture healing
Publication Date：2025-06-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 8-11 )