Analysis of Induction Factors of Arteriovenous Fistula with Loss Function in Patients with Chronic Renal Failure Treated by Hemodialysis

FAN Hong; WU Huashui; LIU Zhoumin

doi:10.14033/j.cnki.cfmr.2025.18.002

Abstract：Objective:To analyze the induction factors of failure of arteriovenous fistula(AVF)in patients with chronic renal failure treated by hemodialysis.Method:62 patients with chronic kidney disease(CKD)admitted to Nanping First Hospital Affiliated to Fujian Medical University from June 2020 to May 2024 were selected for retrospective analysis,and their clinical data were collected.16 patients with failure of AVF and 46 patients whose AVF was not dysfunctional with possible influencing factors were included.Logistic regression analysis was used to screen the factors related to failure of AVF for hemodialysis patients.Result:The blood phosphorus,calcium phosphorus product,platelet(PLT),C-reactive protein(CRP),albumin(ALB)levels and primary disease diabetes,hypotension and thrombosis in the disabled group were higher than those in the non-disabled group,and the proportion of patients with long hemostatic compression time after dialysis was higher than that in the non-disabled group.Logistic regression analysis showed that patients with diabetes,prolonged compression after dialysis,hypotension,thrombosis,and ALB High blood level,high blood phosphorus level,high product of calcium and phosphorus,high CRP level and high PLT level were all risk factors for AVF loss in hemodialysis patients(OR=4.494,1.723,1.682,1.624,1.079,3.239,1.789,3.097,3.095,P<0.05).Conclusion:Diabetes mellitus,low blood pressure,thrombosis,high ALB level,high blood phosphorus level,high calcium-phosphorus product,high CRP level and high PLT level are risk factors for failure of arteriovenous fistula,which can be reduced by the implementation of early effective intervention.